FOXA1 PROMOTES TUMOR PROGRESSION IN PROSTATE CANCER VIA THE INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3 PATHWAY.

FOXA1 promotes tumor progression in prostate cancer via the insulin-like growth factor binding protein 3 pathway.

Fork-head box protein A1 (FOXA1) is a "pioneer factor" that is known to bind to the androgen receptor (AR) and regulate the transcription of AR-specific genes.However, the precise role of FOXA1 in prostate cancer (PC) remains unknown.In this study, we report that FOXA1 plays a critical role in PC cell proliferation.The expression of FOXA1 was highe

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